Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | ATM | Q13315 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017131 | 0.83 | HSP90AA1 (0.63) | HSP90AA1MEN1KMT2AATMCNR1 | |
| SCHEMBL5915328 | 0.81 | HSP90AA1 (0.61) | HSP90AA1MEN1KMT2AATMCNR1 | |
| SCHEMBL5915487 | 0.81 | HSP90AA1 (0.61) | HSP90AA1MEN1KMT2ATRPA1RELA | |
| SCHEMBL38663749 | 0.77 | TRPA1 (0.70) | MEN1KMT2ATRPA1RELANPC1 | |
| SCHEMBL27746923 | 0.77 | TRPA1 (0.70) | MEN1KMT2ATRPA1RELANPC1 | |
| SCHEMBL6735723 | 0.76 | HSP90AA1 (0.53) | HSP90AA1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL6735726 | 0.76 | HSP90AA1 (0.53) | HSP90AA1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL6735720 | 0.76 | HSP90AA1 (0.53) | HSP90AA1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL6597757 | 0.75 | L3MBTL1 (0.59) | HSP90AA1MEN1KMT2AATMCNR1 | |
| SCHEMBL28515985 | 0.75 | TDP1 (0.59) | HSP90AA1MEN1KMT2AATMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |