Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.59 |
| ▸ | CNR2 | P34972 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558082 | 0.85 | TUBB4A (0.53) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL16346288 | 0.85 | TUBB4A (0.53) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL9587486 | 0.83 | HSP90AA1 (0.44) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL7776300 | 0.83 | HSP90AA1 (0.83) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL5792570 | 0.82 | L3MBTL1 (0.49) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL14709198 | 0.80 | L3MBTL1 (0.41) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL1347570 | 0.80 | KDM4E (0.41) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL18805450 | 0.79 | L3MBTL1 (0.59) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL28445468 | 0.79 | APP (0.48) | HSP90AA1ATML3MBTL1TDP1CNR1 | |
| SCHEMBL6597757 | 0.77 | L3MBTL1 (0.59) | HSP90AA1ATML3MBTL1TDP1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |