Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782946 | 0.95 | ALDH1A1 (0.50) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL9811019 | 0.95 | ALDH1A1 (0.50) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL7563341 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL12396105 | 0.82 | ANPEP (0.51) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL4320298 | 0.82 | EPHX2 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL7527715 | 0.82 | EPHX2 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL10714230 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL10713841 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL21225960 | 0.80 | CASP1 (0.54) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL6571074 | 0.80 | CASP1 (0.54) | ALDH1A1HSD17B10PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225911-A1 | ABSORBENT ARTICLE HAVING REAGENTS FOR DETECTING MEDICAL CONDITIONS | BABY RX LLC | 2023-07-20 | — | — | US | disclosed |
| EP-0713093-B1 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER AG (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5663044-A | Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0713093-A2 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | Bayer Corporation (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0157327-B1 | NOVEL COMPOUNDS FOR DETECTING THE PRESENCE OF HYDROLYTIC ANALYTES IN A TEST SAMPLE | MILES INC. (US) | 1991-06-12 | — | — | EP | disclosed |
| EP-0158204-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, CONTAINING A ZWITTERION COUPLING AGENT | MILES INC. (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0157326-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, ESTERASE AND PROTEASE IN A TEST SAMPLE | MILES INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4774340-A | AMINATION, CYCLIZATION, ESTERIFICATION | MILES INC. (US) | 1988-09-27 | — | — | US | disclosed |
| US-4704460-A | LEUKOCYTES IN URINE | MILES LABORATORIES, INC. (US) | 1987-11-03 | — | — | US | disclosed |
| EP-0039880-B2 | AGENTS FOR THE DETECTION OF ESTEROLYTIC AND/OR PROTEOLYTIC ENZYMES; AND PHENOXY-AMINO ACIDS AND PHENOXY-PEPTIDE ESTERS SUITABLE AS SUBSTRATES THEREFOR, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN PRODUCING THE AGENTS | Roche Diagnostics GmbH (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4657855-A | DIP-AND-READ, UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4645842-A | DETECTING LEUKOCYTES TO INDICATE KIDNEY OR UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-02-24 | — | — | US | disclosed |
| US-4637979-A | Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent | MILES LABORATORIES, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0158204-A2 | Composition and test device for determining the presence of leukocytes, containing a zwitterion coupling agent | MILES INC. (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0157327-A2 | Novel compounds for detecting the presence of hydrolytic analytes in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0157326-A2 | Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| US-4499185-A | ANALYSIS FOR LEUKOCYTES USING A CHROMOGENIC ESTER AND 3-QUINUCLIDINOL | MILES LABORATORIES, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0094554-A1 | Test for esterase activity in a liquid sample | MILES LABORATORIES, INC. (US) | 1983-11-23 | — | — | EP | disclosed |