Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782946 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL7776373 | 0.95 | ALDH1A1 (0.55) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL7563341 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL27660507 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL12396105 | 0.78 | ANPEP (0.51) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL7527715 | 0.78 | EPHX2 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL4320298 | 0.78 | EPHX2 (0.57) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL10713841 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL10714230 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL21225960 | 0.76 | CASP1 (0.54) | ALDH1A1HSD17B10PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157327-B1 | NOVEL COMPOUNDS FOR DETECTING THE PRESENCE OF HYDROLYTIC ANALYTES IN A TEST SAMPLE | MILES INC. (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4774340-A | AMINATION, CYCLIZATION, ESTERIFICATION | MILES INC. (US) | 1988-09-27 | — | — | US | disclosed |
| US-4704460-A | LEUKOCYTES IN URINE | MILES LABORATORIES, INC. (US) | 1987-11-03 | — | — | US | disclosed |
| US-4645842-A | DETECTING LEUKOCYTES TO INDICATE KIDNEY OR UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0157327-A2 | Novel compounds for detecting the presence of hydrolytic analytes in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |