Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242690 | 0.90 | MAPT (0.71) | MAPTRAB9ASRD5A2TSHRSMN1; SMN2 | |
| SCHEMBL5608453 | 0.90 | MAPT (0.71) | MAPTRAB9ASRD5A2TSHRSMN1; SMN2 | |
| SCHEMBL7776765 | 0.89 | MAPT (0.71) | MAPTRAB9ASRD5A2FFAR1CYP4A11 | |
| SCHEMBL1928912 | 0.88 | TSHR (0.67) | MAPTRAB9ACYP4A11TSHRCYP4F2 | |
| SCHEMBL7776446 | 0.86 | MAPT (0.51) | MAPTRAB9AFFAR1CYP4A11TSHR | |
| SCHEMBL21656469 | 0.85 | CYP4A11 (0.58) | MAPTRAB9ACYP4A11CYP4F2SMN1; SMN2 | |
| SCHEMBL28345649 | 0.85 | SRD5A2 (0.68) | MAPTRAB9ASRD5A2TSHRSMN1; SMN2 | |
| Diphenylether SCHEMBL10690245 | 0.84 | TSHR (0.79) | MAPTRAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL70185 | 0.84 | CYP4A11 (0.75) | MAPTCYP4A11TSHRCYP4F2SMN1; SMN2 | |
| SCHEMBL17946943 | 0.83 | CA1 (0.60) | MAPTRAB9ACYP4A11CYP4F2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-B1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS INC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |
| US-5530157-A | NON-STEROID ANTIINFLAMMATORY DRUG | SCIOS NOVA INC. (US) | 1996-06-25 | — | — | US | disclosed |