Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | PPARG | P37231 | 4/20 | 0.63 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966681 | 0.94 | MAPT (0.74) | MAPTRAB9APPARGCYP4A11FFAR1 | |
| SCHEMBL4364300 | 0.92 | MAPT (0.74) | MAPTRAB9ACYP4A11FFAR1KDM4E | |
| SCHEMBL7776449 | 0.89 | MAPT (0.64) | MAPTRAB9ACYP4A11FFAR1CYP4F2 | |
| SCHEMBL7776764 | 0.88 | RAB9A (0.65) | MAPTRAB9ACYP4A11FFAR1KDM4E | |
| SCHEMBL4361268 | 0.87 | MAPT (0.72) | MAPTRAB9ACYP4A11FFAR1KDM4E | |
| SCHEMBL5392156 | 0.87 | MAPT (0.77) | MAPTRAB9APPARGCYP4A11FFAR1 | |
| SCHEMBL4359850 | 0.86 | MAPT (0.70) | MAPTRAB9ACYP4A11FFAR1KDM4E | |
| SCHEMBL4376261 | 0.86 | MAPT (0.70) | MAPTRAB9ACYP4A11FFAR1KDM4E | |
| SCHEMBL7774931 | 0.86 | PKM (0.68) | PPARGFFAR1S1PR1S1PR3SRD5A2 | |
| SCHEMBL24844734 | 0.85 | MAPT (0.90) | MAPTRAB9AKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-B1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS INC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |
| US-5530157-A | NON-STEROID ANTIINFLAMMATORY DRUG | SCIOS NOVA INC. (US) | 1996-06-25 | — | — | US | disclosed |