Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 5/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514970 | 0.84 | P2RY6 (0.32) | DUTNT5E | |
| SCHEMBL6363039 | 0.76 | TYMP (0.40) | DUTTYMPSLC6A1SLC6A11 | |
| SCHEMBL917968 | 0.72 | TYMP (0.40) | DUTTYMPSLC6A1SLC6A11 | |
| SCHEMBL917657 | 0.71 | TYMP (0.39) | DUTTYMPSLC6A1SLC6A11 | |
| SCHEMBL2474213 | 0.71 | TYMP (0.34) | DUTTYMPSLC6A1SLC6A11NT5E | |
| SCHEMBL7776573 | 0.71 | DUT (0.41) | DUTTYMPSLC6A1SLC6A11NT5E | |
| SCHEMBL7899020 | 0.69 | TK2 (0.41) | TYMP | |
| SCHEMBL6362956 | 0.69 | P2RY14 (0.39) | TYMPNT5E | |
| SCHEMBL10336769 | 0.69 | NT5E (0.47) | DUTTYMPNT5E | |
| SCHEMBL9109482 | 0.69 | NT5E (0.39) | DUTTYMPSLC6A1SLC6A11NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423839-B1 | Polynucleotides and probes useful in solution phase nucleic acid sandwich assay | BAYER AG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0225807-B1 | Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein | CHIRON CORP (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5093232-A | Detection of dna sequences | CHIRON CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |
| US-4910300-A | Adding additional nucleotide to modified nucleotide at | CHIRON CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |