Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | DUT | P33316 | 7/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776573 | 0.83 | DUT (0.41) | NT5EDUTTYMPSLC6A11SLC6A1 | |
| SCHEMBL9110792 | 0.79 | SLC28A1 (0.41) | NT5EDUTP2RY14 | |
| SCHEMBL13493930 | 0.77 | DUT (0.42) | NT5EDUTTYMPSLC6A11SLC6A1 | |
| SCHEMBL13444851 | 0.77 | DUT (0.60) | DUTTYMPP2RY14 | |
| SCHEMBL13463839 | 0.77 | DUT (0.60) | DUTTYMPP2RY14 | |
| SCHEMBL912656 | 0.77 | DUT (0.60) | DUTTYMPP2RY14 | |
| SCHEMBL912657 | 0.77 | DUT (0.60) | DUTTYMPP2RY14 | |
| SCHEMBL14403996 | 0.77 | DUT (0.60) | DUTTYMPP2RY14 | |
| SCHEMBL19841219 | 0.77 | DUT (0.60) | DUTTYMPP2RY14 | |
| SCHEMBL13575501 | 0.76 | P2RY2 (0.54) | NT5EDUTTYMPP2RY14CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995015332-A1 | TRANSMEMBRANOUS ACTIVE AGENT USED TO DISRUPT DNA BIOSYNTHESIS | ZEPPEZAUER MICHAEL (DE) | 1995-06-08 | — | — | WO | disclosed |