Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295456 | 1.00 | ESR1 (0.59) | ESR1ESR2SRD5A2TSHRDAO | |
| SCHEMBL18077481 | 0.93 | SRD5A2 (0.65) | SRD5A2TSHRRARBRARGRXRA | |
| SCHEMBL5955919 | 0.87 | ALDH1A1 (0.59) | ESR1ESR2SRD5A2TSHRDAO | |
| Benzoic Acid SCHEMBL9258304 | 0.86 | ESR1 (0.70) | ESR1ESR2SRD5A2TSHRDAO | |
| SCHEMBL9514865 | 0.83 | SRD5A2 (0.55) | SRD5A2TSHRDAONAPRTRARB | |
| Benzoic Acid SCHEMBL9155688 | 0.83 | SRD5A2 (0.77) | SRD5A2TSHRDAONAPRTRARB | |
| SCHEMBL20721895 | 0.82 | TSHR (0.59) | SRD5A2TSHRDAONAPRTRARB | |
| SCHEMBL18896444 | 0.82 | TSHR (0.59) | SRD5A2TSHRDAONAPRTRARB | |
| SCHEMBL30354047 | 0.82 | RXRA (0.53) | ESR1ESR2SRD5A2TSHRDAO | |
| Benzoic Acid SCHEMBL11549239 | 0.81 | SRD5A2 (0.74) | SRD5A2TSHRDAONAPRTRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-B1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS INC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |