Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14173702 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL13745224 | 0.80 | CYP2D6 (0.38) | ALDH1A1MEN1KMT2AMAPTGAA | |
| Ethylene SCHEMBL10579767 | 0.80 | TLR4 (0.50) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL12606807 | 0.80 | TLR4 (0.52) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL321283 | 0.80 | TLR4 (0.52) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL10080620 | 0.79 | CYP2D6 (0.37) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL12441829 | 0.77 | TLR4 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL20104022 | 0.77 | TLR4 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL15415140 | 0.76 | TLR4 (0.46) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL4077853 | 0.75 | TLR4 (0.55) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |