Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.43 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489213 | 0.75 | ALDH1A1 (0.48) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL9489209 | 0.75 | ALDH1A1 (0.48) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL1006699 | 0.74 | DPP8 (0.47) | DPP8DPP7DPP4DPP9FAP | |
| Hydrochloric Acid SCHEMBL16909077 | 0.70 | ACE (0.67) | DPP8ACEF2 | |
| SCHEMBL2113410 | 0.69 | DPP7 (0.65) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL2113409 | 0.69 | DPP7 (0.65) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL2123083 | 0.69 | DPP7 (0.65) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL2123080 | 0.69 | DPP7 (0.65) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL29406923 | 0.69 | DPP7 (0.65) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL27796855 | 0.69 | DPP7 (0.65) | DPP8DPP7DPP4DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121600-A2 | METHOD AND SUBSTANCES FOR DIAGNOSIS AND THERAPY OF SEPSIS AND SEPSIS-LIKE SYSTEMIC INFECTIONS | B.R.A.H.M.S Diagnostica GmbH (DE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000022439-A2 | METHOD AND SUBSTANCES FOR DIAGNOSIS AND THERAPY OF SEPSIS AND SEPSIS-LIKE SYSTEMIC INFECTIONS | B.R.A.H.M.S DIAGNOSTICA GMBH (DE) | 2000-04-20 | — | — | WO | disclosed |