Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489213 | 1.00 | ALDH1A1 (0.48) | ALDH1A1DPP8DPP4DPP7NTMT1 | |
| SCHEMBL1006699 | 0.87 | DPP8 (0.47) | DPP8DPP4DPP7NTMT1OPRM1 | |
| SCHEMBL9490722 | 0.84 | DPP8 (0.54) | ALDH1A1DPP8DPP4DPP7NTMT1 | |
| SCHEMBL4889705 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP2C9CYP2C19NPSR1MAPK1 | |
| SCHEMBL7777173 | 0.75 | DPP8 (0.48) | DPP8DPP4DPP7OPRM1OPRD1 | |
| SCHEMBL9488598 | 0.73 | DPP8 (0.51) | ALDH1A1DPP8DPP4DPP7OPRM1 | |
| SCHEMBL29385022 | 0.73 | KDM4E (0.53) | ALDH1A1DPP8DPP4DPP7OPRM1 | |
| SCHEMBL9614454 | 0.73 | KDM4E (0.53) | ALDH1A1DPP8DPP4DPP7OPRM1 | |
| Hydrochloric Acid SCHEMBL29692921 | 0.72 | KDM4E (0.52) | ALDH1A1DPP8DPP4DPP7OPRM1 | |
| SCHEMBL31437669 | 0.72 | NTMT1 (0.50) | ALDH1A1NTMT1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255341-B1 | REAGENT FOR TESTING PERIODONTAL DISEASES | SUNSTAR KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5137811-A | Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria | SUNSTAR KABUSHIKI KAISHA (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0255341-A2 | Reagent for testing periodontal diseases | SUNSTAR KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | disclosed |