Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717803 | 0.94 | — | — | |
| SCHEMBL7772418 | 0.82 | PTGIR (0.47) | — | |
| SCHEMBL7720315 | 0.77 | PTGIR (0.44) | — | |
| SCHEMBL7778642 | 0.76 | PTGER1 (0.40) | ADRA2A | |
| SCHEMBL7055364 | 0.76 | PTGER1 (0.40) | ADRA2A | |
| SCHEMBL7484758 | 0.73 | KMT2A (0.46) | — | |
| SCHEMBL7495469 | 0.73 | KMT2A (0.46) | — | |
| SCHEMBL7776660 | 0.72 | HTR1A (0.33) | — | |
| SCHEMBL7713208 | 0.72 | KMT2A (0.35) | — | |
| SCHEMBL7776663 | 0.72 | HTR1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |