Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055364 | 1.00 | PTGER1 (0.40) | PTGER1PTGER3PTGIRPTGDRADRA2A | |
| SCHEMBL7776620 | 0.81 | PTGIR (0.67) | PTGER1PTGER3PTGIRPTGDR | |
| SCHEMBL7778395 | 0.81 | PTGIR (0.67) | PTGER1PTGER3PTGIRPTGDR | |
| SCHEMBL8481589 | 0.80 | PTGIR (0.56) | PTGER1PTGER3PTGIRPTGDR | |
| SCHEMBL7052348 | 0.78 | PTGIR (0.61) | PTGER1PTGER3PTGIRPTGDR | |
| SCHEMBL7777236 | 0.76 | ADRA2A (0.31) | ADRA2A | |
| SCHEMBL7718293 | 0.75 | — | — | |
| SCHEMBL7713227 | 0.74 | CYP19A1 (0.37) | PTGIRPTGDR | |
| SCHEMBL7718891 | 0.73 | DRD2 (0.36) | PTGIRPTGDR | |
| SCHEMBL7483555 | 0.73 | CYP2A6 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |