Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777366 | 0.86 | NAAA (0.38) | NAAAALDH1A1CNR1GAATRPV1 | |
| SCHEMBL622441 | 0.85 | — | — | |
| SCHEMBL16120784 | 0.85 | CASP2 (0.53) | NAAAALDH1A1CNR1TRPV1SELP | |
| SCHEMBL7775619 | 0.83 | ALDH1A1 (0.36) | NAAAALDH1A1CNR1GAAMEN1 | |
| SCHEMBL9633843 | 0.81 | NAAA (0.56) | NAAAALDH1A1CNR1TRPV1SELP | |
| SCHEMBL7775615 | 0.81 | ALDH1A1 (0.34) | NAAAALDH1A1CNR1GAAMEN1 | |
| SCHEMBL21505016 | 0.80 | CNR1 (0.46) | NAAAALDH1A1CNR1GAATRPV1 | |
| SCHEMBL13876077 | 0.80 | SELP (0.51) | NAAAALDH1A1CNR1TRPV1SELP | |
| SCHEMBL22203694 | 0.79 | HDAC6 (0.35) | NAAAALDH1A1CNR1GAAMEN1 | |
| SCHEMBL10966458 | 0.79 | MEN1 (0.56) | NAAAALDH1A1CNR1TRPV1SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733045-B1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |