SCHEMBL7777374

SCHEMBL7777374

CN(C)C(=O)c1cccc(S(=O)(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.56
LOX P28300 1/20 0.53
TSHR P16473 3/20 0.47
ALDH1A1 P00352 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSD11B1 P28845 1/20 0.46
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
NAMPT P43490 1/20 0.44
ERN1 O75460 2/20 0.43
KIF11 P52732 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
RAB9A P51151 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8305896 0.86 LOX (0.53) AKR1C3LOXALDH1A1HSD17B10TDP1
SCHEMBL3232938 0.84 LOX (0.56) AKR1C3LOXHSD11B1ERN1KIF11
SCHEMBL2822445 0.84 LOX (0.52) AKR1C3LOXALDH1A1HSD17B10TDP1
SCHEMBL20364683 0.81 LOX (0.50) AKR1C3LOXALDH1A1HSD11B1MEN1
SCHEMBL21893019 0.81 LOX (0.50) AKR1C3LOXALDH1A1HSD11B1MEN1
SCHEMBL21893017 0.81 LOX (0.53) AKR1C3LOXHSD11B1MEN1KMT2A
SCHEMBL22836941 0.81 LMNA (0.53) AKR1C3LOXALDH1A1TDP1MEN1
SCHEMBL7406706 0.80 MEN1 (0.55) AKR1C3LOXALDH1A1TDP1MEN1
SCHEMBL19364408 0.80 LOX (0.49) AKR1C3LOXALDH1A1HSD11B1MEN1
SCHEMBL4638087 0.79 ALDH1A1 (0.57) TSHRALDH1A1HSD17B10TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138669-A1 BENZENESULFONIC ACID DERIVATIVE COMPOUNDS, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2001-10-04 EP claimed
EP-1138669-A1 BENZENESULFONIC ACID DERIVATIVE COMPOUNDS, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed