Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ERN1 | O75460 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PMM2 | O15305 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | LOX | P28300 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255459 | 0.91 | MEN1 (0.53) | MEN1KMT2AERN1HPGDALDH1A1 | |
| SCHEMBL12640103 | 0.91 | MEN1 (0.49) | MEN1KMT2AERN1HPGDALDH1A1 | |
| SCHEMBL31365131 | 0.91 | MEN1 (0.49) | MEN1KMT2AERN1HPGDALDH1A1 | |
| SCHEMBL29562303 | 0.89 | PARP1 (0.57) | MEN1KMT2AERN1PMM2MPI | |
| SCHEMBL128134 | 0.89 | PARP1 (0.57) | MEN1KMT2AERN1PMM2MPI | |
| SCHEMBL26966721 | 0.89 | MEN1 (0.47) | MEN1KMT2AERN1HPGDALDH1A1 | |
| SCHEMBL19704270 | 0.88 | MEN1 (0.46) | MEN1KMT2AERN1HPGDALDH1A1 | |
| SCHEMBL2645117 | 0.87 | CA12 (0.57) | MEN1KMT2AERN1ALDH1A1PDK2 | |
| SCHEMBL29628546 | 0.87 | CA12 (0.57) | MEN1KMT2AERN1ALDH1A1PDK2 | |
| SCHEMBL2645114 | 0.87 | ERN1 (0.47) | MEN1KMT2AERN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476743-A | Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant | XEROX CORPORATION (US) | 1995-12-19 | — | — | US | claimed |
| US-20130296605-A1 | Compositions and Methods for Inhibition of Cathepsins | MATEON THERAPEUTICS, INC. | 2013-11-07 | — | — | US | disclosed |
| US-20130296605-A1 | Compositions and Methods for Inhibition of Cathepsins | MATEON THERAPEUTICS, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8039630-B2 | Cationic compound, dye compound and method of using the same, and optical information recording medium | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-8039630-B2 | Cationic compound, dye compound and method of using the same, and optical information recording medium | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20090130367-A1 | CATIONIC COMPOUND, DYE COMPOUND AND METHOD OF USING THE SAME, AND OPTICAL INFORMATION RECORDING MEDIUM | FUJIFILM CORPORATION (JP) | 2009-05-21 | — | — | US | disclosed |
| US-20090130367-A1 | CATIONIC COMPOUND, DYE COMPOUND AND METHOD OF USING THE SAME, AND OPTICAL INFORMATION RECORDING MEDIUM | FUJIFILM CORPORATION (JP) | 2009-05-21 | — | — | US | disclosed |
| US-20090082570-A1 | METHOD OF MANUFACTURING BIPYRIDINIUM COMPOUND AND SYNTHETIC INTERMEDIATE OF THE SAME, METHOD OF MANUFACTURING DYE COMPOUND, AND NOVEL BIPYRIDINIUM COMPOUND AND NOVEL DYE COMPOUND COMPRISING THE SAME | FUJIFILM CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |
| US-20090082570-A1 | METHOD OF MANUFACTURING BIPYRIDINIUM COMPOUND AND SYNTHETIC INTERMEDIATE OF THE SAME, METHOD OF MANUFACTURING DYE COMPOUND, AND NOVEL BIPYRIDINIUM COMPOUND AND NOVEL DYE COMPOUND COMPRISING THE SAME | FUJIFILM CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |
| US-20080274423-A1 | OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION | FUJIFILM CORPORATION (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080274423-A1 | OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION | FUJIFILM CORPORATION (JP) | 2008-11-06 | — | — | US | disclosed |
| US-7420093-B2 | Process for the preparation of glycolaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| US-20080081931-A1 | PROCESS FOR THE PREPARATION OF GLYCOLALDEHYDE | EASTMAN CHEMICAL COMPANY (US) | 2008-04-03 | — | — | US | disclosed |
| EP-0813525-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028427-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-09-19 | — | — | WO | disclosed |
| US-5476743-A | Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant | XEROX CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081931-A1 | PROCESS FOR THE PREPARATION OF GLYCOLALDEHYDE | GRHPR, HRH3, ADH5 | MEN1 3697/4885KMT2A 1955/4885ERN1 4240/4885 |
| US-20090082570-A1 | METHOD OF MANUFACTURING BIPYRIDINIUM COMPOUND AND SYNTHETIC INTERMEDIATE OF THE SAME, METHOD OF MANUFACTURING DYE COMPOUND, AND NOVEL BIPYRIDINIUM COMPOUND AND NOVEL DYE COMPOUND COMPRISING THE SAME | RRS1, RPS3, ADRM1 | MEN1 2975/4885KMT2A 2647/4885ERN1 1938/4885 |
| US-20090130367-A1 | CATIONIC COMPOUND, DYE COMPOUND AND METHOD OF USING THE SAME, AND OPTICAL INFORMATION RECORDING MEDIUM | CHRM1, CHRM2, TRPC6 | MEN1 161/4885KMT2A 2727/4885ERN1 1436/4885 |
| US-20130296605-A1 | Compositions and Methods for Inhibition of Cathepsins | CTSF, CTSS, CTSZ | MEN1 3229/4885KMT2A 4194/4885ERN1 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.