Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883700 | 0.84 | AKR1C1 (0.39) | KCNN4TSHRRAB9AL3MBTL1KMT2A | |
| SCHEMBL7769823 | 0.78 | KCNN4 (0.48) | KCNN4KCNA3TSHRRAB9AL3MBTL1 | |
| SCHEMBL5280949 | 0.78 | KCNN4 (0.48) | KCNN4KCNA3TSHRRAB9AL3MBTL1 | |
| SCHEMBL5481230 | 0.74 | KCNN4 (0.50) | KCNN4KCNA3TSHRRAB9AL3MBTL1 | |
| SCHEMBL15587141 | 0.73 | KCNN4 (0.46) | KCNN4KCNA3TSHRRAB9AL3MBTL1 | |
| SCHEMBL9650536 | 0.70 | CYP2B6 (0.46) | KCNN4TSHRHTR2AKCNH2LMNA | |
| SCHEMBL5479925 | 0.68 | CYP19A1 (0.66) | KCNN4KCNA3TSHRRAB9AL3MBTL1 | |
| SCHEMBL5481989 | 0.67 | KCNN4 (0.49) | KCNN4KCNA3TSHRRAB9AL3MBTL1 | |
| SCHEMBL12856108 | 0.67 | KCNN4 (0.49) | KCNN4KCNA3TSHRRAB9AL3MBTL1 | |
| SCHEMBL2323800 | 0.66 | ADRB1 (0.55) | RAB9ALMNAADRB1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574906-B1 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5380724-A | Inhibitors of lipid peroxidation | GYOGYSZERKUTATO INTEZET KFT (HU) | 1995-01-10 | — | — | US | disclosed |
| EP-0574906-A2 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-12-22 | — | — | EP | disclosed |