Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.49 |
| ▸ | CCKBR | P32239 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280949 | 0.77 | KCNN4 (0.48) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL7769823 | 0.77 | KCNN4 (0.48) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL7777404 | 0.74 | KCNN4 (0.46) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL15587141 | 0.74 | KCNN4 (0.46) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL5479925 | 0.73 | CYP19A1 (0.66) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL3877128 | 0.70 | TRPM5 (0.35) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL11260814 | 0.70 | KCNN4 (0.55) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL5864393 | 0.70 | KCNN4 (0.55) | KCNN4KCNA3KCNH2OPRK1TSHR | |
| SCHEMBL30915985 | 0.69 | MAOA (0.48) | LMNAMAPTALOX15RAB9ASMN1; SMN2 | |
| SCHEMBL12856108 | 0.68 | KCNN4 (0.49) | KCNN4KCNA3KCNH2OPRK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293554-A1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293554-A1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | NFATC1, ORAI1, KCNMA1 | KCNN4 10/4885KCNA3 46/4885KCNH2 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.