Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1059656 | 0.80 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL10823736 | 0.75 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL10371915 | 0.74 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL1826293 | 0.73 | FLT3 (0.55) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL13652067 | 0.73 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL6665885 | 0.72 | MEN1 (0.75) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL3800547 | 0.72 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL5613922 | 0.71 | HPGD (0.53) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL3871617 | 0.71 | TAS1R3 (0.49) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| Hydrochloric Acid SCHEMBL3794175 | 0.71 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001181279-A | BENZOFURANYLPYRROLECARBOXAMIDE DERIVATIVE | MITSUI CHEMICALS INC | 2001-07-03 | — | — | JP | disclosed |