SCHEMBL7777919

SCHEMBL7777919

CCCCC1=Cc2c(cccc2C(C)C)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.38
GABRA1 P14867 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
SLC6A2 P23975 2/20 0.32
HTR2C P28335 2/20 0.32
FAAH O00519 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
GABRB1 P18505 1/20 0.32
PTGS1 P23219 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
HTR2B P41595 1/20 0.32
GABRA2 P47869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7053653 0.84 GABRA1 (0.36) SOAT1GABRA1GABRG2GABRB3SLC6A2
SCHEMBL5954076 0.78 ADRA2A (0.37) SLC6A2HTR2CLMNADRD2HTR2A
SCHEMBL2970251 0.78 DRD2 (0.33) SLC6A2HTR2CDRD2HTR2ASLC6A4
SCHEMBL2968517 0.74 HTR2A (0.37) SLC6A2HTR2CCYP1A2DRD2HTR2A
SCHEMBL29287787 0.74 SOAT1 (0.35) SOAT1SLC6A2HTR2CDRD2HTR2A
SCHEMBL7047520 0.73 GABRA1 (0.40) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL2957327 0.73 HTR2A (0.39) SLC6A2HTR2CLMNACYP1A2CYP3A4
SCHEMBL2970470 0.73 HTR2A (0.39) SLC6A2HTR2CLMNACYP1A2CYP3A4
SCHEMBL2972150 0.73 HTR2A (0.39) SLC6A2HTR2CLMNACYP1A2CYP3A4
SCHEMBL2965963 0.73 HTR2A (0.39) SLC6A2HTR2CLMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1227271-C Solid catalytic composition for olefin polymerization ATOCHEM ELF SA (FR) 2005-11-16 CN disclosed
EP-0889065-B1 Solid catalyst component for the polymerisation of olefins ATOFINA (FR) 2001-08-22 EP disclosed
US-6057258-A Solid catalytic component for the polymerization of olefins ELF ATOCHEM S.A. (FR) 2000-05-02 US disclosed
EP-0889065-A1 Solid catalyst component for the polymerisation of olefins ELF ATOCHEM S.A. (FR) 1999-01-07 EP disclosed
CN-1203924-A Solid catalytic composition for olefin polymerization ATOCHEM ELF SA (FR) 1999-01-06 CN disclosed