SCHEMBL7778263

SCHEMBL7778263

Cc1c(OC(=O)O)n[nH]c1O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.35
HCAR3 P49019 1/20 0.35
DAO P14920 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8338423 0.78 ALDH1A1 (0.40) HCAR2
SCHEMBL7234538 0.68 HCAR2 (0.57) HCAR2HCAR3DAO
SCHEMBL15971926 0.66 MAPT (0.49)
SCHEMBL11526298 0.65 LMNA (0.33)
SCHEMBL9336496 0.64 KDM4E (0.32)
SCHEMBL377052 0.64 KDM4E (0.36)
SCHEMBL9213204 0.64 KDM4C (0.56) HCAR2
SCHEMBL2922727 0.63 HSD17B10 (0.31)
SCHEMBL7401096 0.63 HCAR2 (0.31) HCAR2HCAR3
SCHEMBL725505 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1127050-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2001-08-29 EP disclosed
WO-2000027821-A1 METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed