Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | MAX | P61244 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342620 | 0.93 | BRD4 (0.50) | BRD4SGMS2MEN1KMT2ATDP1 | |
| SCHEMBL7345964 | 0.90 | LMNA (0.49) | MEN1KMT2AGAA | |
| SCHEMBL7342119 | 0.85 | SGMS2 (0.46) | BRD4SGMS2MEN1KMT2AGAA | |
| SCHEMBL7338831 | 0.83 | PYGL (0.47) | MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL7344642 | 0.82 | HDAC1 (0.43) | BRD4MEN1KMT2AGAAHDAC1 | |
| SCHEMBL7344138 | 0.82 | GAA (0.42) | BRD4GAA | |
| SCHEMBL7778567 | 0.81 | KDM4E (0.55) | TDP1L3MBTL1 | |
| SCHEMBL7348561 | 0.78 | TP53 (0.39) | L3MBTL1GAA | |
| SCHEMBL7344390 | 0.78 | RXFP1 (0.42) | MEN1KMT2AGAA | |
| SCHEMBL1497381 | 0.78 | EGFR (0.46) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |