Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.62 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694553 | 0.88 | TSPO (0.72) | TSPOLTB4R2TSHRALDH1A1NPC1 | |
| SCHEMBL8976804 | 0.85 | LMNA (0.49) | TSPOLTB4R2ACHEGAATSHR | |
| SCHEMBL6727472 | 0.84 | RNF4 (0.53) | TSPOLTB4R2HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL1336855 | 0.82 | TSHR (0.49) | LTB4R2GAATSHRALDH1A1NPC1 | |
| SCHEMBL14176611 | 0.81 | TSPO (0.73) | TSPOLTB4R2ALDH1A1NPC1GLA | |
| SCHEMBL4822461 | 0.80 | TSPO (0.62) | TSPOLTB4R2ALDH1A1NPC1GLA | |
| SCHEMBL8001968 | 0.80 | TSPO (0.67) | TSPOLTB4R2ALDH1A1NPC1GLA | |
| SCHEMBL8009661 | 0.80 | TSPO (0.62) | TSPOLTB4R2ALDH1A1NPC1GLA | |
| SCHEMBL3060251 | 0.79 | TSHR (0.71) | LTB4R2ACHEGAATSHRALDH1A1 | |
| SCHEMBL943042 | 0.79 | TSPO (0.60) | TSPOLTB4R2ALDH1A1NPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129084-A2 | PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2001-09-05 | — | — | EP | claimed |
| WO-2000027832-A2 | THIAZOLE DERIVATIVES AS PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-05-18 | — | — | WO | claimed |
| EP-4265613-A1 | BENZENE RING COMPOUND AND USE THEREOF | Nanjing Shijiang Medicine Technology Co., Ltd (CN) | 2023-10-25 | — | — | EP | disclosed |
| EP-1129084-A2 | PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027832-A2 | THIAZOLE DERIVATIVES AS PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |