Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432596 | 0.87 | ALDH1A1 (0.55) | TSHRTSPONPC1ALDH1A1GLA | |
| SCHEMBL7778393 | 0.85 | TSPO (0.62) | GAATSHRCYP3A4MAPTTSPO | |
| SCHEMBL1336855 | 0.76 | TSHR (0.49) | LMNAGAATSHRCYP1A2CYP3A4 | |
| SCHEMBL5182572 | 0.74 | NR1H2 (0.50) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9168266 | 0.74 | CYP2C19 (0.59) | LMNATSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3060251 | 0.73 | TSHR (0.71) | GAATSHRMAPTNPC1ALDH1A1 | |
| SCHEMBL18590698 | 0.72 | KCNA3 (0.49) | LMNAGAATSHRCYP1A2CYP3A4 | |
| SCHEMBL12096794 | 0.71 | ALDH1A1 (0.63) | LMNATSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1927016 | 0.71 | ALDH1A1 (0.69) | GAATSHRTSPONPC1ALDH1A1 | |
| SCHEMBL18532307 | 0.71 | MGLL (0.61) | LMNAGAATSHRALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706512-A1 | ACETAMIDE DERIVATIVES AND THEIR USE FOR MODIFYING FEEDING BEHAVIOUR MODIFIERS | LABORATOIRE L. LAFON (FR) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001333-A1 | ACETAMIDE DERIVATIVES AND THEIR USE FOR MODIFYING FEEDING BEHAVIOUR MODIFIERS | LABORATOIRE L. LAFON (FR) | 1995-01-12 | — | — | WO | disclosed |