Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.58 |
| ▸ | PGK2 | P07205 | 2/20 | 0.58 |
| ▸ | ACP3 | P15309 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14114290 | 0.88 | PGK1 (0.73) | PGK1PGK2ACP3CA1MMP2 | |
| Hydrochloric Acid SCHEMBL10915162 | 0.86 | PGK1 (0.71) | PGK1PGK2ACP3CA1MMP2 | |
| SCHEMBL11650654 | 0.85 | PGK1 (0.54) | PGK1PGK2ACP3CA1MMP2 | |
| SCHEMBL10701108 | 0.80 | PGK1 (0.49) | PGK1PGK2ACP3CA1MMP2 | |
| Phosphoric Acid SCHEMBL28200180 | 0.79 | PGK1 (0.61) | PGK1PGK2ACP3CA1MMP2 | |
| SCHEMBL28504463 | 0.78 | PGK1 (0.47) | PGK1PGK2ACP3CA1MMP2 | |
| SCHEMBL8164654 | 0.78 | PGK1 (0.51) | PGK1PGK2ACP3CA1MMP2 | |
| SCHEMBL12229763 | 0.77 | ACP3 (0.49) | PGK1PGK2ACP3CA1MMP2 | |
| SCHEMBL7775624 | 0.72 | CA12 (0.47) | PGK1PGK2MMP2CA12CES2 | |
| SCHEMBL62723 | 0.72 | TSHR (0.67) | CES2MGLLTSHRMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673944-B1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-16 | — | — | EP | claimed |
| CN-109096334-B | Preparation method of chiral aryl phosphine oxide compound and derivative thereof | 广西大学 | 2021-01-15 | — | — | CN | disclosed |
| US-9493494-B2 | Phosphinine oxide derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2016-11-15 | — | — | US | disclosed |
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | PHOSPHO1, PPIP5K2, ITPA | PGK1 1214/4885PGK2 704/4885ACP3 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.