SCHEMBL7778985

SCHEMBL7778985

CC1C(=O)Oc2cc3ccccc3cc21

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
POLB P06746 1/20 0.38
CASP6 P55212 1/20 0.38
HSP90AA1 P07900 1/20 0.37
PAX8 Q06710 1/20 0.37
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 3/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
LMNA P02545 1/20 0.34
NPC1 O15118 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
DHODH Q02127 1/20 0.33
ALDH2 P05091 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15147092 0.76 MAOA (0.45) GAASMN1; SMN2NPSR1
SCHEMBL29473842 0.76 MAOA (0.45) GAASMN1; SMN2NPSR1
SCHEMBL2407012 0.76 MAOA (0.45) GAASMN1; SMN2NPSR1
SCHEMBL14852681 0.75 ALDH1A1 (0.47) GAAPOLBMAPTSMN1; SMN2ALDH1A1
SCHEMBL7778971 0.75 GAA (0.34) GAAMAPTALDH1A1
SCHEMBL7778978 0.74 PGR (0.39) GAAALDH1A1ALDH2
SCHEMBL11062247 0.73 PRKD3 (0.38) HSP90AA1MAPTNPSR1
SCHEMBL7785526 0.72 GAA (0.58) GAAALDH1A1HPGDALDH2
SCHEMBL31409184 0.72 ALDH1A1 (0.46) GAAMAPTALDH1A1ALDH2
SCHEMBL18952097 0.72 ALDH1A1 (0.46) GAAMAPTALDH1A1ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707575-B1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH & CIE (CH) 2001-10-24 EP claimed
EP-0707575-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH SA (CH) 1996-04-24 EP claimed
WO-1995030667-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH S.A. (CH) 1995-11-16 WO claimed
EP-0707575-B1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH & CIE (CH) 2001-10-24 EP disclosed