Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KLK7 | P49862 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779915 | 0.85 | ELANE (0.46) | ELANELMNAKMT2A | |
| SCHEMBL7779017 | 0.85 | ELANE (0.46) | ELANESMN1; SMN2KMT2A | |
| SCHEMBL7779935 | 0.83 | FAAH (0.45) | ELANE | |
| SCHEMBL7777587 | 0.83 | ELANE (0.47) | ELANEALDH1A1LMNAKDM4E | |
| SCHEMBL7778739 | 0.82 | ELANE (0.48) | ELANELMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL7776777 | 0.81 | ELANE (0.45) | ELANELMNAKLK7SMN1; SMN2KMT2A | |
| SCHEMBL7778734 | 0.81 | ELANE (0.47) | ELANEALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL8781490 | 0.81 | ELANE (0.44) | ELANELMNAKMT2ACNR2 | |
| SCHEMBL7779931 | 0.81 | ELANE (0.44) | ELANELMNAKMT2ACNR2 | |
| SCHEMBL8746491 | 0.78 | ELANE (0.66) | ELANEALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809627-B1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 2001-09-12 | — | — | EP | disclosed |
| US-6025507-A | Borneol derivatives, methods of manufacturing them, and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |
| WO-1996025392-A1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |