Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12863513 | 0.87 | RXFP1 (0.59) | EPHX2DHODHTGM2RXFP1ALDH1A1 | |
| SCHEMBL3415035 | 0.85 | EPHX2 (0.66) | EPHX2DHODHTGM2ALDH1A1TRPV1 | |
| SCHEMBL2518624 | 0.85 | EPHX2 (0.76) | EPHX2DHODHTGM2ALDH1A1TRPV1 | |
| SCHEMBL439393 | 0.84 | RXFP1 (0.74) | RXFP1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL9078037 | 0.84 | RXFP1 (0.59) | EPHX2RXFP1ALDH1A1TRPV1RAB9A | |
| SCHEMBL13274217 | 0.81 | EPHX2 (0.59) | EPHX2DHODHTGM2ALDH1A1TRPV1 | |
| SCHEMBL669442 | 0.81 | EPHX2 (0.70) | EPHX2DHODHTGM2ALDH1A1TRPV1 | |
| SCHEMBL10040308 | 0.81 | DHODH (0.66) | EPHX2DHODHTGM2ALDH1A1TRPV1 | |
| SCHEMBL8401862 | 0.81 | DHODH (0.66) | EPHX2DHODHTGM2ALDH1A1TRPV1 | |
| SCHEMBL7535310 | 0.80 | TDP1 (0.62) | RXFP1ALDH1A1RAB9AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107151224-A | A kind of synthetic method of the alkyl-indol ketone derivatives of 3 methyl 3 | 江苏理工学院 | 2017-09-12 | — | — | CN | claimed |
| CN-107151224-A | A kind of synthetic method of the alkyl-indol ketone derivatives of 3 methyl 3 | 江苏理工学院 | 2017-09-12 | — | — | CN | disclosed |
| CN-106831509-A | A kind of synthetic method of Bicalutamide | 西北师范大学 | 2017-06-13 | — | — | CN | disclosed |
| EP-1124795-A1 | INHIBITORS OF THE EGF-RECEPTOR TYROSINE KINASE AND THEIR USE | Parker Hughes Institute (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000056703-A1 | INHIBITORS OF THE EGF-RECEPTOR TYROSINE KINASE AND THEIR USE | PARKER HUGHES INSTITUTE (US) | 2000-09-28 | — | — | WO | disclosed |