Sugi Predict

Sugi Predict / Compounds / SCHEMBL777917

SCHEMBL777917

SCHEMBL777917

CS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 11/20 0.50
▸ CA2 P00918 11/20 0.50
▸ CA12 O43570 5/20 0.50
▸ CA7 P43166 5/20 0.50
▸ CA13 Q8N1Q1 5/20 0.50
▸ MMP1 P03956 1/20 0.43
▸ MMP2 P08253 1/20 0.43
▸ MMP9 P14780 1/20 0.43
▸ MMP8 P22894 1/20 0.43
▸ MMP13 P45452 1/20 0.43
▸ F2 P00734 3/20 0.39
▸ PRSS1 P07477 3/20 0.39
▸ PRSS2 P07478 3/20 0.39
▸ PRSS3 P35030 3/20 0.39
▸ CA9 Q16790 3/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ GRIN2D O15399 1/20 0.30
▸ GRIN3B O60391 1/20 0.30
▸ GRIN1 Q05586 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12433063 0.97 CA1 (0.45) CA1CA2CA12CA7CA13
SCHEMBL23802285 0.87 CA1 (0.40) CA1CA2CA12CA7CA13
SCHEMBL107769 0.85 CA1 (0.38) CA1CA2CA12CA7CA13
SCHEMBL24460050 0.83 CA1 (0.42) CA1CA2CA12CA7CA13
SCHEMBL2759901 0.83 CA1 (0.39) CA1CA2CA12CA7CA13
SCHEMBL20226554 0.83 CA1 (0.42) CA1CA2CA12CA7CA13
SCHEMBL31124445 0.83 CA1 (0.36) CA1CA2CA12CA7CA13
SCHEMBL24843790 0.81 CA1 (0.40) CA1CA2CA12CA7CA13
SCHEMBL24459976 0.81 CA1 (0.41) CA1CA2CA12CA7CA13
SCHEMBL1457197 0.81 CA1 (0.40) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 — — US disclosed
WO-2024175998-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF DUNAD THERAPEUTICS, LTD. (GB) 2024-08-29 — — WO disclosed
US-20240018153-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO, INC. (CA) 2024-01-18 — — US disclosed
US-20240018153-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO, INC. (CA) 2024-01-18 — — US disclosed
EP-4247787-A2 METHODS AND COMPOSITION FOR KRAS MODIFICATIONS 2692372 Ontario, Inc. (CA) 2023-09-27 — — EP disclosed
CN-116745264-A Methods and compositions for KRAS modification 2692372安大略公司 2023-09-12 — — CN disclosed
CN-116745268-A Benzenesulfonamide derivatives and uses thereof 2692372安大略公司 2023-09-12 — — CN disclosed
EP-3377484-B1 METHODS FOR TREATING MULTIPLE SCLEROSIS USING PYRIMIDINE AND PYRIDINE COMPOUNDS WITH BTK INHIBITORY ACTIVITY MERCK PATENT GMBH (DE) 2023-09-06 — — EP disclosed
US-20230006155-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-01-05 — — US disclosed
EP-4014977-A1 PYRIMIDINE COMPOUNDS WITH BTK INHIBITORY ACTIVITY FOR USE IN TREATING CANCER Merck Patent GmbH (DE) 2022-06-22 — — EP disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 — — US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 — — US disclosed
US-20090209422-A1 Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives BAYER CROPSCIENCE AG (DE) 2009-08-20 — — US disclosed
US-20090209422-A1 Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives BAYER CROPSCIENCE AG (DE) 2009-08-20 — — US disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 — — EP disclosed
US-7378154-B2 Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 — — US disclosed
US-20070218289-A1 Photofunctional Laminated Article DAIKIN INDUSTRIES, LTD. (JP) 2007-09-20 — — US disclosed
US-20070197718-A1 Photofunctional optical material comprising fluorine-containing acrylate polymer DAIKIN INDUSTRIES LTD. 2007-08-23 — — US disclosed
US-20070072136-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. 2007-03-29 — — US disclosed
US-7195856-B2 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2007-03-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209422-A1 Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives DDT, AADAC, DDC CA1 4570/4885CA2 3457/4885CA12 4867/4885
US-20240018153-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF ABCG2, ABCB1, ARSA CA1 4541/4885CA2 3215/4885CA12 2893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.