Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12251273 | 0.76 | ALDH1A1 (0.45) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL3445944 | 0.73 | ALDH1A1 (0.47) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL18377967 | 0.72 | ALDH1A1 (0.41) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL24945812 | 0.71 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL24425171 | 0.69 | ALDH1A1 (0.36) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL22043099 | 0.68 | ALDH1A1 (0.38) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL13167790 | 0.68 | RAPGEF4 (0.41) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL11114149 | 0.67 | ALDH1A1 (0.47) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL5848266 | 0.66 | AKR1C2 (0.55) | TSHRALDH1A1HSD17B10CYP3A4HPGD | |
| SCHEMBL12251322 | 0.66 | MAPK1 (0.41) | TSHRALDH1A1HSD17B10CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |