SCHEMBL7779402

SCHEMBL7779402

[2H]C1([2H])CC(c2ccc(OCC)cc2)CC([2H])([2H])C1=O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.45
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
LMNA P02545 2/20 0.41
HRH3 Q9Y5N1 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.40
NPC1 O15118 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
SENP8 Q96LD8 1/20 0.40
NLRP3 Q96P20 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4602856 0.83 HRH3 (0.56) NQO1MAOAMAOBLMNAHRH3
SCHEMBL9586183 0.82 NQO1 (0.61) NQO1MAOAMAOBHRH3MAPT
SCHEMBL10017473 0.78 NQO1 (0.50) NQO1MAOAMAOBMAPTRAB9A
SCHEMBL9349628 0.78 NQO1 (0.50) NQO1MAOAMAOBMAPTRAB9A
SCHEMBL12960814 0.78 HRH3 (0.55) NQO1LMNAHRH3MAPTNPC1
SCHEMBL7002551 0.77 HRH3 (0.47) NQO1MAOAMAOBLMNAHRH3
SCHEMBL7782189 0.77 NQO1 (0.41) NQO1MAOAMAOBLMNAMAPT
SCHEMBL7779567 0.77 MAOA (0.44) NQO1MAOAMAOBLMNAHRH3
SCHEMBL30368557 0.77 MAPT (0.52) NQO1MAOAMAOBLMNAMAPT
SCHEMBL10484596 0.76 HTT (0.45) NQO1MAOAMAOBLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637623-B1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK & CHEMICALS (JP) 2001-10-04 EP disclosed
EP-0637623-A1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-02-08 EP disclosed