SCHEMBL7782189

SCHEMBL7782189

[2H]C1([2H])CC(c2ccc(OCC)cc2)CC([2H])([2H])C1C=O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.41
MAPT P10636 1/20 0.39
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
ACACB O00763 2/20 0.37
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782972 0.87 NQO1 (0.40) NQO1MAPTMAOAMAOBACACB
SCHEMBL7775218 0.86 NQO1 (0.45) NQO1MAPTMAOAMAOBACACB
SCHEMBL9586183 0.79 NQO1 (0.61) NQO1MAPTMAOAMAOBTSHR
SCHEMBL7779517 0.78 NQO1 (0.42) NQO1MAPTMAOAMAOBLMNA
SCHEMBL7779402 0.77 NQO1 (0.45) NQO1MAPTMAOAMAOBLMNA
SCHEMBL7782402 0.77 NQO1 (0.41) NQO1MAPTMAOAMAOBTSHR
SCHEMBL16985038 0.75 RAB9A (0.54) MAOAMAOBLMNARAB9ANPC1
SCHEMBL7779437 0.74 NQO1 (0.39) NQO1MAPTMAOAMAOBACACB
SCHEMBL12960814 0.74 HRH3 (0.55) NQO1MAPTLMNAALDH1A1GAA
SCHEMBL15274896 0.74 NQO1 (0.45) NQO1MAPTMAOAMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637623-B1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK & CHEMICALS (JP) 2001-10-04 EP disclosed
EP-0637623-A1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-02-08 EP disclosed