SCHEMBL7779567

SCHEMBL7779567

[2H]C1CC(=O)CC([2H])([2H])C1c1ccc(OCC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
LMNA P02545 1/20 0.42
NQO1 P15559 1/20 0.41
MAPK1 P28482 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
HTT P42858 2/20 0.37
NPC1 O15118 1/20 0.37
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
SENP8 Q96LD8 1/20 0.37
NLRP3 Q96P20 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 2/20 0.36
ACACB O00763 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4602856 0.80 HRH3 (0.56) MAOAMAOBLMNANQO1MAPK1
SCHEMBL7779402 0.77 NQO1 (0.45) MAOAMAOBLMNANQO1MAPK1
SCHEMBL7002551 0.74 HRH3 (0.47) MAOAMAOBLMNANQO1MAPK1
SCHEMBL7782189 0.73 NQO1 (0.41) MAOAMAOBLMNANQO1NPC1
SCHEMBL30368557 0.73 MAPT (0.52) MAOAMAOBLMNANQO1MAPK1
SCHEMBL7782065 0.72 NQO1 (0.40) MAOAMAOBLMNANQO1MAPK1
SCHEMBL7782972 0.72 NQO1 (0.40) MAOAMAOBLMNANQO1NPC1
SCHEMBL7779517 0.72 NQO1 (0.42) MAOAMAOBLMNANQO1MAPK1
SCHEMBL9586183 0.71 NQO1 (0.61) MAOAMAOBNQO1HRH3RAB9A
SCHEMBL7782180 0.71 NQO1 (0.39) MAOAMAOBLMNANQO1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637623-B1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK & CHEMICALS (JP) 2001-10-04 EP disclosed
EP-0637623-A1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-02-08 EP disclosed