Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.46 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782410 | 1.00 | SLC6A1 (0.46) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| Fumaric Acid SCHEMBL11257527 | 0.92 | SLC6A1 (0.40) | SLC6A1SLC6A12SLC6A11DRD2HTR2A | |
| Ramciclane SCHEMBL2108206 | 0.82 | SLC6A1 (0.64) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11257896 | 0.80 | SLC6A1 (0.56) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL7780678 | 0.80 | SLC6A1 (0.56) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11252330 | 0.79 | SLC6A1 (0.49) | SLC6A1SLC6A12SLC6A11HSD17B3CHRM1 | |
| SCHEMBL11253836 | 0.77 | SLC6A1 (0.45) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11241358 | 0.76 | SLC6A1 (0.50) | SLC6A1SLC6A12SLC6A11HSD17B3CHRM1 | |
| SCHEMBL11251756 | 0.74 | SLC6A1 (0.46) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11245908 | 0.73 | SLC6A1 (0.45) | SLC6A1SLC6A12SLC6A11CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | claimed |
| EP-0694299-A1 | The use of( a) bicycloheptane derivative(s) | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-31 | — | — | EP | claimed |
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | disclosed |
| EP-0694299-B1 | The use of( a) bicycloheptane derivative(s) | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2001-09-19 | — | — | EP | disclosed |
| EP-0694299-A1 | The use of( a) bicycloheptane derivative(s) | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | HTR2A, HTR2C, CYP3A43 | SLC6A1 507/4885SLC6A12 1460/4885SLC6A11 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.