Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.45 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780678 | 0.87 | SLC6A1 (0.56) | SLC6A1SLC6A12SLC6A11OPRM1SLC6A2 | |
| SCHEMBL11257896 | 0.87 | SLC6A1 (0.56) | SLC6A1SLC6A12SLC6A11OPRM1SLC6A2 | |
| SCHEMBL11251756 | 0.83 | SLC6A1 (0.46) | SLC6A1SLC6A12SLC6A11OPRM1SLC6A2 | |
| Ramciclane SCHEMBL2108206 | 0.83 | SLC6A1 (0.64) | SLC6A1SLC6A12SLC6A11OPRM1 | |
| SCHEMBL11253836 | 0.82 | SLC6A1 (0.45) | SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL11241358 | 0.79 | SLC6A1 (0.50) | SLC6A1SLC6A12SLC6A11OPRM1SLC6A2 | |
| SCHEMBL11252330 | 0.78 | SLC6A1 (0.49) | SLC6A1SLC6A12SLC6A11CHRM2CHRM1 | |
| SCHEMBL11251560 | 0.77 | SLC6A1 (0.46) | SLC6A1SLC6A12SLC6A11 | |
| Fumaric Acid SCHEMBL11262713 | 0.77 | ALDH1A1 (0.41) | SLC6A1SLC6A12SLC6A11OPRM1SLC6A2 | |
| SCHEMBL11257165 | 0.74 | SIGMAR1 (0.43) | SLC6A1SLC6A12SLC6A11USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342762-A | USEFUL AS TRANQUILIZERS, ANALGESICS, ANTIEPILEPTIC AGENTS, AND AS A TREATMENT FOR PARKINSON'S DISEASE | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |