Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.56 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.56 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257896 | 1.00 | SLC6A1 (0.56) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| Ramciclane SCHEMBL2108206 | 0.93 | SLC6A1 (0.64) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11251560 | 0.89 | SLC6A1 (0.46) | SLC6A1SLC6A12SLC6A11HRH3KCNH2 | |
| SCHEMBL11251756 | 0.89 | SLC6A1 (0.46) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11253836 | 0.88 | SLC6A1 (0.45) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11245908 | 0.87 | SLC6A1 (0.45) | SLC6A1SLC6A12SLC6A11CHRM2CHRM1 | |
| SCHEMBL11241358 | 0.84 | SLC6A1 (0.50) | SLC6A1SLC6A12SLC6A11CHRM2CHRM1 | |
| SCHEMBL11252330 | 0.83 | SLC6A1 (0.49) | SLC6A1SLC6A12SLC6A11CHRM2CHRM1 | |
| Fumaric Acid SCHEMBL11262713 | 0.82 | ALDH1A1 (0.41) | SLC6A1SLC6A12SLC6A11SCN1ASCN2A | |
| SCHEMBL11262967 | 0.82 | SLC6A1 (0.53) | SLC6A1SLC6A12SLC6A11HRH3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694299-B1 | The use of( a) bicycloheptane derivative(s) | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2001-09-19 | — | — | EP | claimed |
| EP-0694299-A1 | The use of( a) bicycloheptane derivative(s) | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-31 | — | — | EP | claimed |
| EP-0694299-B1 | The use of( a) bicycloheptane derivative(s) | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2001-09-19 | — | — | EP | disclosed |
| EP-0694299-A1 | The use of( a) bicycloheptane derivative(s) | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-31 | — | — | EP | disclosed |