SCHEMBL7782972

SCHEMBL7782972

[2H]C1([2H])CC(c2ccc(OCC)cc2)CC([2H])([2H])C1([2H])C=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.40
MAPT P10636 1/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
PIM1 P11309 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
ESR2 Q92731 1/20 0.36
ACACB O00763 2/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782189 0.87 NQO1 (0.41) NQO1MAPTRAB9ANPC1MAOA
SCHEMBL7775218 0.79 NQO1 (0.45) NQO1MAPTRAB9AMAOAMAOB
SCHEMBL7782402 0.78 NQO1 (0.41) NQO1MAPTRAB9ANPC1MAOA
SCHEMBL9586183 0.78 NQO1 (0.61) NQO1MAPTRAB9AMAOAMAOB
SCHEMBL7779517 0.77 NQO1 (0.42) NQO1MAPTRAB9ANPC1MAOA
SCHEMBL7779402 0.76 NQO1 (0.45) NQO1MAPTRAB9ANPC1MAOA
SCHEMBL7779437 0.73 NQO1 (0.39) NQO1MAPTRAB9ANPC1MAOA
SCHEMBL12960814 0.73 HRH3 (0.55) NQO1MAPTRAB9ANPC1ALDH1A1
SCHEMBL7779567 0.72 MAOA (0.44) NQO1MAPTRAB9ANPC1MAOA
SCHEMBL4602856 0.72 HRH3 (0.56) NQO1MAPTRAB9ANPC1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637623-B1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK & CHEMICALS (JP) 2001-10-04 EP disclosed
EP-0637623-A1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-02-08 EP disclosed