Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186352 | 0.79 | HDAC2 (0.72) | MEN1KMT2ARAB9ALMNAKDM4E | |
| SCHEMBL17117265 | 0.76 | HPGD (0.61) | ALDH1A1LMNASMN1; SMN2HPGDHDAC2 | |
| SCHEMBL3199145 | 0.76 | LMNA (0.66) | MEN1KMT2ARAB9ALMNAKDM4E | |
| SCHEMBL6290165 | 0.76 | HPGD (0.66) | MEN1KMT2ARAB9ALMNAKDM4E | |
| SCHEMBL8744900 | 0.76 | HPGD (0.81) | MEN1KMT2ARAB9ALMNAKDM4E | |
| SCHEMBL3681101 | 0.76 | CNR2 (0.68) | MEN1KMT2ARAB9ALMNAKDM4E | |
| SCHEMBL10963359 | 0.74 | HPGD (0.64) | MEN1KMT2ARAB9ALMNAKDM4E | |
| SCHEMBL4517102 | 0.74 | HPGD (0.64) | MEN1KMT2ARAB9ALMNAKDM4E | |
| SCHEMBL6360887 | 0.74 | HPGD (0.79) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL7779895 | 0.74 | HPGD (0.64) | MEN1KMT2ARAB9ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688314-B1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AG (DE) | 2001-10-04 | — | — | EP | disclosed |