Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860351 | 0.95 | ALDH1A1 (0.50) | ALDH1A1POLBAKR1C3RECQLMAPT | |
| SCHEMBL11039515 | 0.75 | ALDH1A1 (0.76) | ALDH1A1POLBRECQLMAPTLMNA | |
| SCHEMBL7787262 | 0.74 | ALDH1A1 (0.47) | ALDH1A1POLBRECQLMAPTLMNA | |
| SCHEMBL7787265 | 0.74 | ALDH1A1 (0.47) | ALDH1A1POLBRECQLMAPTLMNA | |
| SCHEMBL7785009 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNANPSR1TDP1 | |
| SCHEMBL7444744 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBRECQLLMNASMN1; SMN2 | |
| SCHEMBL5860388 | 0.72 | ALDH1A1 (0.52) | ALDH1A1POLBRECQLMAPTLMNA | |
| SCHEMBL5632562 | 0.71 | ALDH1A1 (0.51) | ALDH1A1POLBRECQLMAPTLMNA | |
| SCHEMBL27901118 | 0.71 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTLMNASMN1; SMN2 | |
| SCHEMBL5861424 | 0.70 | ALDH1A1 (0.42) | ALDH1A1POLBMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |