Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787262 | 1.00 | ALDH1A1 (0.47) | ALDH1A1POLBHPGDRAB9AAR | |
| SCHEMBL5861612 | 0.94 | ALDH1A1 (0.50) | ALDH1A1POLBHPGDRAB9AAR | |
| SCHEMBL9196067 | 0.81 | CES2 (0.42) | ALDH1A1POLBRAB9ARECQLKMT2A | |
| SCHEMBL7444744 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBHPGDRAB9AAR | |
| SCHEMBL11039515 | 0.77 | ALDH1A1 (0.76) | ALDH1A1POLBRAB9AARRECQL | |
| SCHEMBL5632562 | 0.75 | ALDH1A1 (0.51) | ALDH1A1POLBARRECQLKMT2A | |
| SCHEMBL7780053 | 0.74 | ALDH1A1 (0.47) | ALDH1A1POLBRECQLKMT2AMAPT | |
| SCHEMBL5860161 | 0.73 | POLB (0.49) | ALDH1A1POLBRAB9ARECQLKMT2A | |
| SCHEMBL11841515 | 0.73 | ALDH1A1 (0.56) | ALDH1A1POLBRAB9AARKMT2A | |
| SCHEMBL27901118 | 0.72 | ALDH1A1 (0.52) | ALDH1A1POLBHPGDRAB9AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |