SCHEMBL7780085

SCHEMBL7780085

C=CC(=O)N(C(N)=O)C(=O)NCO

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
FGFR4 P22455 1/20 0.32
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567032 0.76 ALDH1A1 (0.47) ALDH1A1TSHRFGFR4
Acrylamide SCHEMBL9129476 0.66 TSHR (0.55) ALDH1A1TSHRFGFR4MAPK1TDP1
SCHEMBL181176 0.65 LMNA (0.44) ALDH1A1TSHRFGFR4MAPK1TDP1
Carbamic Acid SCHEMBL29060326 0.64 ALDH1A1 (0.54) ALDH1A1TSHRFGFR4MAPK1TDP1
SCHEMBL30879936 0.64 ALDH1A1 (0.39) ALDH1A1TSHRFGFR4
Acrylamide SCHEMBL7036616 0.64 TSHR (0.54) ALDH1A1TSHRFGFR4MAPK1TDP1
SCHEMBL8607630 0.63 ALDH1A1 (0.43) ALDH1A1TSHRFGFR4
SCHEMBL3622188 0.63 LMNA (0.41) ALDH1A1TSHRFGFR4MAPK1TDP1
SCHEMBL8841270 0.63 ALDH1A1 (0.31) ALDH1A1MAPK1
SCHEMBL25806 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1132734-A1 METHOD OF PREPARING ELECTROPHORETIC SUPPORT, ELECTROPHORETIC MATRIX AND METHOD OF ELECTROPHORESIS Riken (JP) 2001-09-12 EP disclosed