SCHEMBL181176

SCHEMBL181176

C=CC(=O)N(C(=O)C=C)C(=O)C=C

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
FGFR4 P22455 1/20 0.41
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3622188 0.96 LMNA (0.41) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL8743203 0.83 LMNA (0.44) LMNAALDH1A1TSHRFGFR4
SCHEMBL6379416 0.81 ALDH1A1 (0.47) LMNAALDH1A1TSHRFGFR4
SCHEMBL9567032 0.81 ALDH1A1 (0.47) LMNAALDH1A1TSHRFGFR4
SCHEMBL372525 0.81 ALDH1A1 (0.47) LMNAALDH1A1TSHRFGFR4
SCHEMBL2446840 0.81 LMNA (0.30) LMNA
SCHEMBL8607630 0.76 ALDH1A1 (0.43) LMNAALDH1A1TSHRFGFR4
SCHEMBL4359317 0.74 ALDH1A1 (0.46) LMNAALDH1A1TSHRTDP1
SCHEMBL28441938 0.74 ALDH1A1 (0.41) LMNAALDH1A1TSHRTDP1
SCHEMBL7203144 0.74 ALDH1A1 (0.41) LMNAALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 970 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049219-A1 REACTIVE GEL MATERIAL FOR SUSTAINED WATER-BASED REACTIONS EVERBOND INTERFACE TECHNOLOGIES INC. (CA) 2026-02-19 US claimed
EP-4636398-A2 REACTIVE GEL MATERIAL FOR SUSTAINED WATER-BASED REACTIONS Everbond Interface Technologies, Inc. (CA) 2025-10-22 EP claimed
EP-4617656-A2 REACTIVE GEL MATERIAL FOR SUSTAINED WATER-BASED REACTIONS Everbond Interface Technologies, Inc. (CA) 2025-09-17 EP claimed
EP-4532607-A1 REACTIVE GEL MATERIAL FOR SUSTAINED WATER-BASED REACTIONS Everbond Interface Technologies, Inc. (CA) 2025-04-09 EP claimed
WO-2024129672-A1 TRAFFICKED RNAS FOR ASSESSMENT OF CELL-CELL CONNECTIVITY AND NEUROANATOMY THE BROAD INSTITUTE, INC. (US) 2024-06-20 WO claimed
US-20240043915-A1 METHODS AND COMPOSITIONS FOR IN SITU MACROMOLECULE DETECTION AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2024-02-08 US claimed
US-20240016706-A1 MATERIALS FOR OBTURATION SONENDO, INC. 2024-01-18 US claimed
CN-113164882-B Membrane for selective substance delivery 科德宝两合公司 2023-12-22 CN claimed
WO-2023230720-A1 REACTIVE GEL MATERIAL FOR SUSTAINED WATER-BASED REACTIONS EVERBOND INTERFACE TECHNOLOGIES, INC. (CA) 2023-12-07 WO claimed
WO-2023110783-A1 POLYMER FOR DETECTING ALDEHYDES AND KETONES AGROSUP (FR) 2023-06-22 WO claimed
WO-2010062678-A2 MICRO-SPHERICAL POROUS BIOCOMPATIBLE SCAFFOLDS AND METHODS AND APPARATUS FOR FABRICATING SAME LIU DAVID (US) 2010-06-03 WO claimed
WO-2010046084-A1 MACROPOROUS POLYMERIC CROSSLINKED MATERIALS, METHOD FOR MANUFACTURE THEREOF AND USE STICHTING DUTCH POLYMER INSTITUTE (NL) 2010-04-29 WO claimed
EP-2179751-A1 Macroporous polymeric crosslinked materials, method for manufacture thereof and use Stichting Dutch Polymer Institute (NL) 2010-04-28 EP claimed
US-6627720-B2 Monoethylenically unsaturated monomers are polymerized with at least one multiethylenically unsaturated monomer at high temperatures by free radical polymerization in a continuous reactor, without formation of highly crosslinked gels JOHNSON POLYMER, LLC 2003-09-30 US claimed
US-6265511-B1 BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER S. C. JOHNSON COMMERICAL MARKETS, INC. 2001-07-24 US claimed
EP-0241132-B1 COMPOSITIONS SUITABLE IN OR AS FILM, COATING, MASTIC, ADHESIVE, CAULK COMPOSITIONS, AND A METHOD OF MAKING THEM ROHM AND HAAS COMPANY (US) 1991-07-03 EP claimed
EP-0405464-A2 Polyether acrylamide derivatives and active energy ray curable resin composition AJINOMOTO CO., INC. (JP) 1991-01-02 EP claimed
US-4863990-A Modified solution polymers for coatings, films, mastics, caulks, and adhesives ROHM AND HAAS COMPANY (US) 1989-09-05 US claimed
EP-0241132-A2 Compositions suitable in or as film, coating, mastic, adhesive, caulk compositions, and a method of making them ROHM AND HAAS COMPANY (US) 1987-10-14 EP claimed
US-4043819-A Photo-polymerizable material for the preparation of stable polymeric images and process for making them by photopolymerization in a matrix CIBA-GEIGY AG (CH) 1977-08-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049219-A1 REACTIVE GEL MATERIAL FOR SUSTAINED WATER-BASED REACTIONS DSG1, CTSG, PARG LMNA 1232/4885ALDH1A1 3781/4885TSHR 2222/4885
US-20240016706-A1 MATERIALS FOR OBTURATION ACR, GMPS, AAAS LMNA 3013/4885ALDH1A1 225/4885TSHR 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.