Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780187 | 0.89 | HTR2B (0.36) | RAB9AHTR2CHTR2BHTR2AMEN1 | |
| SCHEMBL7776071 | 0.86 | S1PR1 (0.35) | S1PR1 | |
| SCHEMBL7782557 | 0.85 | CETP (0.45) | HTR2CHTR2BHTR2AMEN1KMT2A | |
| SCHEMBL7776065 | 0.79 | S1PR1 (0.41) | S1PR1RAB9AHTR2CHTR2BHTR2A | |
| SCHEMBL7783750 | 0.78 | SLC6A2 (0.33) | — | |
| SCHEMBL7782554 | 0.75 | EGFR (0.45) | RAB9AHTR2CHTR2BHTR2AMEN1 | |
| SCHEMBL7781130 | 0.74 | NR3C2 (0.33) | GPR52GRIN1 | |
| SCHEMBL7780260 | 0.74 | RXRA (0.43) | MEN1KMT2ACNR1 | |
| SCHEMBL7776064 | 0.74 | HTR2B (0.46) | HTR2CHTR2BHTR2AGPR52 | |
| SCHEMBL31750237 | 0.74 | HTR2B (0.46) | HTR2CHTR2BHTR2AGPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |