Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780178 | 0.89 | S1PR1 (0.39) | HTR2BHTR2CHTR2AGRIN1GPR52 | |
| SCHEMBL7782557 | 0.86 | CETP (0.45) | HTR2BHTR2CHTR2ATAAR1GPR52 | |
| SCHEMBL7781130 | 0.85 | NR3C2 (0.33) | GRIN1GRIN2BGPR52 | |
| SCHEMBL7776063 | 0.82 | MMP13 (0.31) | SIGMAR1SLC6A4 | |
| SCHEMBL7780184 | 0.78 | KDR (0.40) | HTR2BHTR2CHTR2ATAAR1GPR52 | |
| SCHEMBL7780257 | 0.78 | KDR (0.43) | RAB9AMEN1KMT2ALMNAMAPT | |
| SCHEMBL7782554 | 0.76 | EGFR (0.45) | HTR2BHTR2CHTR2ATAAR1GPR52 | |
| SCHEMBL7776065 | 0.71 | S1PR1 (0.41) | HTR2BHTR2CHTR2AGPR52RAB9A | |
| SCHEMBL7783750 | 0.71 | SLC6A2 (0.33) | SIGMAR1LMNASLC6A4 | |
| SCHEMBL7776064 | 0.70 | HTR2B (0.46) | HTR2BHTR2CHTR2ATAAR1GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |