Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776071 | 0.87 | S1PR1 (0.35) | SLC6A2SLC6A4SLC6A3LMNAMLYCD | |
| SCHEMBL7776063 | 0.84 | MMP13 (0.31) | SLC6A2SLC6A4SLC6A3MLYCDTMEM97 | |
| SCHEMBL7782557 | 0.84 | CETP (0.45) | SLC6A4LMNAPOLBSIGMAR1CSF1R | |
| SCHEMBL7780178 | 0.78 | S1PR1 (0.39) | — | |
| SCHEMBL7780260 | 0.77 | RXRA (0.43) | SLC6A2SLC6A4SLC6A3PTPN5ATM | |
| SCHEMBL7780253 | 0.72 | RAF1 (0.41) | EGFRTNNI3K | |
| SCHEMBL7776068 | 0.72 | PYCR1 (0.38) | SLC6A2SLC6A4SLC6A3LMNAATM | |
| SCHEMBL7780187 | 0.71 | HTR2B (0.36) | SLC6A4LMNASIGMAR1 | |
| SCHEMBL7781130 | 0.70 | NR3C2 (0.33) | KCNH2 | |
| SCHEMBL7776059 | 0.69 | CNR2 (0.33) | SLC6A2SLC6A4SLC6A3LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |