SCHEMBL7780205

SCHEMBL7780205

CCOC(CCO)N(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769092 0.80
SCHEMBL5442524 0.80 THRB (0.36) THRBLMNA
SCHEMBL5933658 0.76 THRB (0.33) THRBLMNA
SCHEMBL27853222 0.76 THRB (0.33) THRBLMNA
SCHEMBL11291743 0.76 MEN1 (0.34) THRBLMNA
SCHEMBL5437352 0.76 DNM1 (0.33) THRBLMNA
SCHEMBL1065510 0.76 MAPT (0.39) LMNA
SCHEMBL6860268 0.76 MEN1 (0.32) LMNA
SCHEMBL11423706 0.74 THRB (0.32) THRBLMNA
SCHEMBL4272344 0.74 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015087094-A1 NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES SEMMELWEIS EGYETEM (HU) 2015-06-18 WO disclosed
EP-0718695-B1 Water-developable photosensitive resin composition NIPPON PAINT CO LTD (JP) 2001-09-19 EP disclosed
US-5837421-A POLYMERS FOR FLEXOGRAPHIC PRINTING PLATES MADE FROM DIENE MONOMERS AND ACRYLATE MONOMERS FOR IMPACT STRENGTH NIPPON PAINT CO., LTD. (JP) 1998-11-17 US disclosed
EP-0718695-A2 Water-developable photosensitive resin composition Nippon Paint Co., Ltd. (JP) 1996-06-26 EP disclosed