Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | FADS1 | O60427 | 2/20 | 0.33 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787598 | 0.93 | MAPKAPK2 (0.43) | MEN1KMT2APOLBMAPKAPK2GSK3B | |
| SCHEMBL7784990 | 0.92 | POLB (0.46) | MEN1KMT2APOLBMAPKAPK2CASR | |
| SCHEMBL7785121 | 0.91 | MAPKAPK2 (0.46) | MEN1KMT2APOLBMAPKAPK2GSK3B | |
| SCHEMBL7780305 | 0.90 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7785270 | 0.90 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7787653 | 0.90 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7787635 | 0.89 | MEN1 (0.38) | MEN1KMT2APOLBMAPKAPK2CASR | |
| SCHEMBL7785293 | 0.89 | MAPKAPK2 (0.40) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7784925 | 0.89 | ALDH1A1 (0.41) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7787745 | 0.89 | MAPKAPK2 (0.41) | MEN1KMT2APOLBMAPKAPK2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |