SCHEMBL7780452

SCHEMBL7780452

CCCCN(CCCC)c1ccc(C(c2ccc(N(CCCC)CCCC)cc2)c2ccc(N(C)C)cc2C(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.46
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 1/20 0.46
CNR2 P34972 7/20 0.45
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
PTPN11 Q06124 1/20 0.36
PTPRO Q16827 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
IDO1 P14902 1/20 0.35
SLC16A3 O15427 1/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7780465 0.94 ALDH1A1 (0.51) GAAALDH1A1KDM4EPOLBCNR2
SCHEMBL7778519 0.93 CNR2 (0.43) GAAALDH1A1KDM4EPOLBCNR2
SCHEMBL7781204 0.90 ALDH1A1 (0.48) GAAALDH1A1KDM4EPOLBCNR2
SCHEMBL7773670 0.90 ALDH1A1 (0.48) GAAALDH1A1KDM4EPOLBCNR2
SCHEMBL7778136 0.87 ALDH1A1 (0.44) GAAALDH1A1KDM4EPOLBCNR2
SCHEMBL10999527 0.86 ALDH1A1 (0.43) GAAALDH1A1KDM4EPOLBCNR2
SCHEMBL7778141 0.84 ALDH1A1 (0.45) GAAALDH1A1KDM4EPOLBCNR2
SCHEMBL7778133 0.84 ALDH1A1 (0.43) GAAALDH1A1KDM4ECNR2KMT2A
SCHEMBL7780597 0.82 MCL1 (0.39) GAAALDH1A1KMT2ATDP1L3MBTL1
SCHEMBL7780490 0.82 ALDH1A1 (0.39) GAAALDH1A1KDM4ECNR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885892-B1 Preparation process of phthalide compound MITSUI CHEMICALS INC (JP) 2001-09-19 EP disclosed
US-5973168-A Preparation process of phthalide compound MITSUI CHEMICALS, INC. (JP) 1999-10-26 US disclosed
EP-0885892-A1 Preparation process of phthalide compound Mitsui Chemicals, Inc. (JP) 1998-12-23 EP disclosed