Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781204 | 0.96 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EPOLBCNR2 | |
| SCHEMBL7773670 | 0.96 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EPOLBCNR2 | |
| SCHEMBL7780452 | 0.94 | GAA (0.46) | ALDH1A1GAAKDM4EPOLBCNR2 | |
| SCHEMBL7778164 | 0.86 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EPOLBCNR2 | |
| SCHEMBL7778519 | 0.86 | CNR2 (0.43) | ALDH1A1GAAKDM4EPOLBCNR2 | |
| SCHEMBL7778133 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4ECNR2KMT2A | |
| SCHEMBL8324518 | 0.80 | L3MBTL1 (0.44) | ALDH1A1GAAKDM4ECNR2KMT2A | |
| SCHEMBL7778136 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EPOLBCNR2 | |
| SCHEMBL10999527 | 0.79 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4EPOLBCNR2 | |
| SCHEMBL655214 | 0.76 | CNR2 (0.49) | ALDH1A1GAAKDM4EPOLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885892-B1 | Preparation process of phthalide compound | MITSUI CHEMICALS INC (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5973168-A | Preparation process of phthalide compound | MITSUI CHEMICALS, INC. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0885892-A1 | Preparation process of phthalide compound | Mitsui Chemicals, Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |